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Reconstitute each vial of PLUSET FLEX H with 10 ml of the PLUSET diluent provided. Subcutaneous administration results in an irregular absorption and must be avoided. The injection of PLUSET FLEX H must be intra-muscular (i.m.).

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There are no ascertained contra-indications.ĭo not slaughter animals for human consumption for 10 days following the last injection.īroken or cracked vials should be handled with gloves. Kinetic studies of FSH and LH in the bloodstream of bovine has shown a half-life of 150 minutes for FSH and a half-life of 40 minutes for LH.įor the induction of superovulation in bovine females. PLUSET FLEX H is manufactured in a method chosen to ensure that the defined level of LH content is consistently mantained. Thus, given that it influences the activity of FSH, it is important to have a defined level of LH present. The pituitary hormone extract contains variable levels of Follicle-Stimulating Hormone (FSH) and Luteinizing Hormone (LH).Ĭlearly in order to obtain proper and effective superovulation which provides satisfactory results involving a high number of living embryos, it is necessary to carry out a treatment that guarantees the activation and progress of multiple follicle maturation in the most “physiological” and repeatable way possible. Ovarian stimulation with exogenous Follicle-Stimulating Hormone (FSH) allows a greater number of ova to be produced than normally produced in a single reproductive cycle.

In the absence of an International Standard for the porcine gonadotrophin, dosing is carried out using the International Standard for human urine FSH and LH.

The use of standardized concentrations for both gonadotrophins guarantees a consistent quality of the product and eliminates possible variability in effectiveness from one lot to another. PLUSET FLEX H is a mixture of swine pituitary gonadotrophins used for the induction of multiple ovulations (superovulation). For further information about unapproved drugs, click here.

PLUSET FLEX H- porcine follicle stimulating hormone, porcine luteinizing hormoneĭisclaimer: This drug has not been found by FDA to be safe and effective, and this labeling has not been approved by FDA.

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